NMT2

Entrez Summary: N/A
UniProt Summary: Adds a myristoyl group to the N-terminal glycine residue of certain cellular and viral proteins. {ECO:0000269|PubMed:25255805, ECO:0000269|PubMed:9506952}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

NMT
NMT C

glycylpeptide N-tetradecanoyltransferase activity
N-terminal peptidyl-glycine N-myristoylation
peptidyl-glycine modification
protein myristoylation
N-terminal protein myristoylation
N-terminal protein lipidation
regulation of rhodopsin mediated signaling pathway
N-terminal protein amino acid modification
intracellular transport of virus
host cell
transport of virus
extrinsic component of membrane
multi-organism transport
multi-organism localization
protein lipidation
lipoprotein biosynthetic process
lipoprotein metabolic process
regulation of G protein-coupled receptor signaling pathway
protein acylation
viral life cycle
viral process
symbiotic process
interspecies interaction between organisms
peptidyl-amino acid modification
Golgi apparatus
regulation of response to external stimulus
organonitrogen compound biosynthetic process
cellular macromolecule biosynthetic process
macromolecule biosynthetic process