NOXRED1

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
39°C R06 exp303	-1.81
Ibrutinib 10μM R08 exp442	1.86

pyrroline-5-carboxylate reductase activity
L-proline biosynthetic process
proline biosynthetic process
proline metabolic process
glutamine family amino acid biosynthetic process
alpha-amino acid biosynthetic process
glutamine family amino acid metabolic process
cellular amino acid biosynthetic process
alpha-amino acid metabolic process
carboxylic acid biosynthetic process
organic acid biosynthetic process
cellular amino acid metabolic process
cellular component
drug metabolic process
small molecule biosynthetic process
molecular function
carboxylic acid metabolic process
oxidation-reduction process
oxoacid metabolic process
organic acid metabolic process
heterocycle biosynthetic process
organic cyclic compound biosynthetic process
organonitrogen compound biosynthetic process
small molecule metabolic process