NPTXR

Entrez Summary: N/A
UniProt Summary: May be involved in mediating uptake of synaptic material during synapse remodeling or in mediating the synaptic clustering of AMPA glutamate receptors at a subset of excitatory synapses. {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

regulation of postsynaptic neurotransmitter receptor activity
cytoplasmic side of plasma membrane
filopodium
regulation of neurotransmitter receptor activity
growth cone
regulation of nervous system process
regulation of signaling receptor activity
glutamatergic synapse
neuronal cell body
dendrite
modulation of chemical synaptic transmission
regulation of trans-synaptic signaling
regulation of system process
neuron projection development
neuron development
neuron differentiation
plasma membrane bounded cell projection organization
cell projection organization
generation of neurons
neurogenesis
cell development