NT5C1A

Entrez Summary: N/A
UniProt Summary: Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides and has a broad substrate specificity. Helps to regulate adenosine levels in heart during ischemia and hypoxia. {ECO:0000269|PubMed:11133996}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

purine nucleoside monophosphate catabolic process
nucleoside monophosphate catabolic process
adenosine metabolic process
5-nucleotidase activity
pyrimidine nucleoside catabolic process
nucleoside catabolic process
pyrimidine nucleoside metabolic process
purine nucleoside monophosphate metabolic process
pyrimidine-containing compound catabolic process
glycosyl compound catabolic process
purine nucleotide catabolic process
nucleobase-containing small molecule catabolic process
purine-containing compound catabolic process
purine ribonucleoside metabolic process
nucleotide binding
purine nucleoside metabolic process
nucleotide catabolic process
nucleoside phosphate catabolic process
nucleoside monophosphate metabolic process
ribonucleoside metabolic process
nucleobase-containing small molecule biosynthetic process
pyrimidine-containing compound metabolic process
nucleoside metabolic process
organophosphate catabolic process
glycosyl compound metabolic process
carbohydrate derivative catabolic process
magnesium ion binding
dephosphorylation
purine nucleotide metabolic process
purine-containing compound metabolic process
nucleobase-containing compound catabolic process
heterocycle catabolic process
cellular nitrogen compound catabolic process
small molecule catabolic process
aromatic compound catabolic process
nucleotide metabolic process
nucleoside phosphate metabolic process
organic cyclic compound catabolic process
drug metabolic process
nucleobase-containing small molecule metabolic process