OGN

Entrez Summary: N/A
UniProt Summary: Induces bone formation in conjunction with TGF-beta-1 or TGF-beta-2.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

keratan sulfate catabolic process
extracellular matrix structural constituent conferring compression resistance
keratan sulfate biosynthetic process
keratan sulfate metabolic process
negative regulation of smooth muscle cell proliferation
extracellular vesicle
sulfur compound catabolic process
glycosaminoglycan catabolic process
aminoglycan catabolic process
lysosomal lumen
Golgi lumen
glycosaminoglycan biosynthetic process
mucopolysaccharide metabolic process
aminoglycan biosynthetic process
regulation of smooth muscle cell proliferation
glycosaminoglycan metabolic process
growth factor activity
aminoglycan metabolic process
sulfur compound biosynthetic process
carbohydrate derivative catabolic process
collagen-containing extracellular matrix
sulfur compound metabolic process
carbohydrate derivative biosynthetic process
negative regulation of cell population proliferation
oxoacid metabolic process
organic acid metabolic process
carbohydrate derivative metabolic process
macromolecule catabolic process
organonitrogen compound catabolic process
organonitrogen compound biosynthetic process
extracellular space
regulation of cell population proliferation
small molecule metabolic process
macromolecule biosynthetic process
organic substance catabolic process
cellular catabolic process
extracellular region