OR56A1
Gene Information
- Official Symbol: OR56A1
- Official Name: olfactory receptor family 56 subfamily A member 1
- Aliases and Previous Symbols: N/A
- Entrez ID: 120796
- UniProt: Q8NGH5
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: N/A
Function Summary
- Entrez Summary: N/A
- UniProt Summary: Odorant receptor. {ECO:0000305}.
Pfam Domains GO Terms
Pfam Domains
| 7TM GPCR Srsx |
| 7tm 1 |
GO Terms
| dopamine neurotransmitter receptor activity, coupled via Gi/Go |
| adenylate cyclase-inhibiting dopamine receptor signaling pathway |
| dopamine binding |
| adrenergic receptor activity |
| synaptic transmission, dopaminergic |
| behavioral response to cocaine |
| adenylate cyclase-activating adrenergic receptor signaling pathway |
| adrenergic receptor signaling pathway |
| dopamine receptor signaling pathway |
| regulation of dopamine secretion |
| response to cocaine |
| regulation of catecholamine secretion |
| response to anesthetic |
| adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway |
| cellular response to dopamine |
| response to dopamine |
| signal transduction involved in cellular response to ammonium ion |
| regulation of amine transport |
| regulation of response to drug |
| cellular response to monoamine stimulus |
| cellular response to catecholamine stimulus |
| response to monoamine |
| response to catecholamine |
| response to alkaloid |
| adenylate cyclase-activating G protein-coupled receptor signaling pathway |
| cellular response to ammonium ion |
| adult behavior |
| cAMP-mediated signaling |
| cyclic-nucleotide-mediated signaling |
| response to ammonium ion |
| adenylate cyclase-modulating G protein-coupled receptor signaling pathway |
| G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger |
| response to xenobiotic stimulus |
| second-messenger-mediated signaling |
| cellular response to drug |
| anterograde trans-synaptic signaling |
| chemical synaptic transmission |
| trans-synaptic signaling |
| detection of chemical stimulus involved in sensory perception of smell |
| olfactory receptor activity |
| synaptic signaling |
| sensory perception of smell |
| detection of chemical stimulus involved in sensory perception |
| detection of chemical stimulus |
| sensory perception of chemical stimulus |
| cellular response to organic cyclic compound |
| detection of stimulus involved in sensory perception |
| behavior |
| cellular response to organonitrogen compound |
| cellular response to nitrogen compound |
| detection of stimulus |
| regulation of ion transport |
| regulation of secretion by cell |
| regulation of secretion |
| response to organic cyclic compound |
| sensory perception |
| response to organonitrogen compound |
| response to drug |
| cellular response to oxygen-containing compound |
| response to nitrogen compound |
| cell-cell signaling |
| cellular response to endogenous stimulus |
| G protein-coupled receptor signaling pathway |
| nervous system process |
| integral component of plasma membrane |
| response to endogenous stimulus |
| response to oxygen-containing compound |
| intracellular signal transduction |
| regulation of transport |
| system process |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
No hits were found.
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Essentiality in NALM6
- Essentiality Rank: 17121
- Expression level (log2 read counts): -7.68
Expression Distribution
OR56A1 Expression in NALM6 Cells: -7.68