PCSK2

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Peptidase S8
P proprotein

enkephalin processing
islet amyloid polypeptide processing
insulin processing
insulin metabolic process
protein autoprocessing
peptide hormone processing
secretory granule
transport vesicle
perikaryon
protein processing
serine-type endopeptidase activity
hormone metabolic process
protein maturation
protein-containing complex binding
neuron projection
dendrite
peptide metabolic process
regulation of hormone levels
intracellular membrane-bounded organelle
cellular amide metabolic process
proteolysis
extracellular space
membrane
gene expression