PDIA6

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

peptide disulfide oxidoreductase activity
endoplasmic reticulum chaperone complex
protein disulfide isomerase activity
IRE1-mediated unfolded protein response
endoplasmic reticulum-Golgi intermediate compartment
cell redox homeostasis
melanosome
endoplasmic reticulum unfolded protein response
cellular response to unfolded protein
cellular response to topologically incorrect protein
response to unfolded protein
response to topologically incorrect protein
protein folding
response to endoplasmic reticulum stress
endoplasmic reticulum lumen
post-translational protein modification
cellular homeostasis
endoplasmic reticulum membrane
oxidation-reduction process
endoplasmic reticulum
extracellular space
homeostatic process
cellular response to stress