PDXDC1

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
Mdivi-1 15μM R05 exp217	1.7
2-Methoxyestradiol 0.55μM R07 exp310	1.77

sphinganine-1-phosphate aldolase activity
carboxy-lyase activity
sphingolipid catabolic process
membrane lipid catabolic process
pyridoxal phosphate binding
sphingolipid metabolic process
ameboidal-type cell migration
cellular lipid catabolic process
membrane lipid metabolic process
lipid catabolic process
cadherin binding
intracellular membrane-bounded organelle
carboxylic acid metabolic process
cellular lipid metabolic process
cell migration
Golgi apparatus
oxoacid metabolic process
endoplasmic reticulum
organic acid metabolic process
organonitrogen compound catabolic process
cell motility
localization of cell
lipid metabolic process
locomotion
movement of cell or subcellular component
small molecule metabolic process
organic substance catabolic process
cellular catabolic process