PILRB

Entrez Summary: N/A
UniProt Summary: Paired receptors consist of highly related activating and inhibitory receptors and are widely involved in the regulation of the immune system. PILRB is thought to act as a cellular signaling activating receptor that associates with ITAM-bearing adapter molecules on the cell surface.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

activation of transmembrane receptor protein tyrosine kinase activity
MHC class I protein binding
activation of protein kinase activity
transmembrane receptor protein tyrosine kinase signaling pathway
positive regulation of protein kinase activity
positive regulation of kinase activity
positive regulation of transferase activity
enzyme linked receptor protein signaling pathway
regulation of protein kinase activity
cellular protein-containing complex assembly
regulation of kinase activity
regulation of transferase activity
positive regulation of protein phosphorylation
positive regulation of phosphorylation
positive regulation of phosphorus metabolic process
positive regulation of phosphate metabolic process
regulation of immune response
positive regulation of protein modification process
integral component of plasma membrane
positive regulation of catalytic activity
regulation of protein phosphorylation
protein-containing complex assembly
regulation of phosphorylation
positive regulation of cellular protein metabolic process
regulation of immune system process
positive regulation of protein metabolic process
positive regulation of molecular function
regulation of phosphate metabolic process
regulation of phosphorus metabolic process
regulation of protein modification process
protein-containing complex subunit organization