PKP3

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

desmosome assembly
alpha-catenin binding
desmosome organization
messenger ribonucleoprotein complex
translation regulator activity
cadherin binding involved in cell-cell adhesion
desmosome
negative regulation of mRNA catabolic process
cell adhesion molecule binding
negative regulation of RNA catabolic process
cornified envelope
negative regulation of mRNA metabolic process
cell-cell adherens junction
cell-cell junction assembly
cornification
cell-cell junction organization
cell junction assembly
cell-cell junction
protein localization to plasma membrane
regulation of mRNA catabolic process
cell junction organization
protein localization to cell periphery
keratinization
negative regulation of cellular catabolic process
keratinocyte differentiation
negative regulation of catabolic process
cadherin binding
epidermal cell differentiation
regulation of mRNA metabolic process
enzyme binding
regulation of translation
skin development
regulation of cellular amide metabolic process
epidermis development
protein localization to membrane
cell-cell adhesion
posttranscriptional regulation of gene expression
cell junction
epithelial cell differentiation
regulation of cellular catabolic process