PLD4

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 1/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

PLDc
PLD envelope

N-acylphosphatidylethanolamine-specific phospholipase D activity
phospholipase D activity
inositol phosphate metabolic process
phagocytic vesicle
hematopoietic progenitor cell differentiation
trans-Golgi network membrane
polyol metabolic process
lipid catabolic process
alcohol metabolic process
phagocytosis
organic hydroxy compound metabolic process
hemopoiesis
hematopoietic or lymphoid organ development
immune system development
organophosphate metabolic process
endoplasmic reticulum membrane
endoplasmic reticulum
lipid metabolic process
small molecule metabolic process
organic substance catabolic process
vesicle-mediated transport