PLEKHG5

• Official Symbol: PLEKHG5
• Official Name: pleckstrin homology and RhoGEF domain containing G5
• Aliases and Previous Symbols: N/A
• Entrez ID: 57449
• UniProt: O94827
• Interactions: BioGRID
• PubMed articles: Open PubMed
• OMIM: Open OMIM

• Entrez Summary: This gene encodes a protein that activates the nuclear factor kappa B (NFKB1) signaling pathway. Mutations in this gene are associated with autosomal recessive distal spinal muscular atrophy. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012].
• UniProt Summary: N/A

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

• Essentiality Rank: 2731
• Expression level (log2 read counts): 0.33

Expression Distribution

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PLEKHG5 Expression in NALM6 Cells: 0.33