PLS1

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

CH
efhand

terminal web assembly
intestinal D-glucose absorption
terminal web
intestinal hexose absorption
regulation of microvillus length
actin filament network formation
actin filament bundle
regulation of cell projection size
regulation of microvillus organization
positive regulation of multicellular organism growth
intestinal absorption
cortical actin cytoskeleton organization
cortical cytoskeleton organization
brush border
positive regulation of protein localization to plasma membrane
positive regulation of protein localization to cell periphery
actin filament bundle assembly
actin filament bundle organization
regulation of multicellular organism growth
digestive system process
carbohydrate transport
actin filament
regulation of protein localization to plasma membrane
structural constituent of cytoskeleton
digestion
regulation of protein localization to cell periphery
positive regulation of protein localization to membrane
positive regulation of developmental growth
regulation of protein localization to membrane
actin filament binding
actin filament organization
positive regulation of growth
positive regulation of cellular protein localization
regulation of developmental growth
regulation of cellular component size
supramolecular fiber organization
actin cytoskeleton organization
regulation of anatomical structure size
regulation of cellular protein localization
actin filament-based process