PREP

Gene Information
  • Official Symbol: PREP
  • Official Name: prolyl endopeptidase
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 5550
  • UniProt: P48147
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: The protein encoded by this gene is a cytosolic prolyl endopeptidase that cleaves peptide bonds on the C-terminal side of prolyl residues within peptides that are up to approximately 30 amino acids long. Prolyl endopeptidases have been reported to be involved in the maturation and degradation of peptide hormones and neuropeptides. [provided by RefSeq, Jul 2008].
  • UniProt Summary: Cleaves peptide bonds on the C-terminal side of prolyl residues within peptides that are up to approximately 30 amino acids long.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 10745
  • Expression level (log2 read counts): 5.86

Expression Distribution

  • Last modified: 2026/01/07 22:36
  • by 127.0.0.1