PTPRA

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
ABT-702 5μM plus Deferoxamine 11μM R07 exp321	-2.18
GSK461364A 0.005μM R03 exp125	1.95
MLN-4924 0.2μM R00 exp21	2.22

integral component of synaptic membrane
transmembrane receptor protein tyrosine phosphatase activity
Schaffer collateral - CA1 synapse
insulin receptor signaling pathway
protein tyrosine phosphatase activity
peptidyl-tyrosine dephosphorylation
cellular response to insulin stimulus
receptor complex
protein dephosphorylation
response to insulin
axon guidance
neuron projection guidance
cellular response to peptide hormone stimulus
dephosphorylation
cellular response to peptide
MAPK cascade
axonogenesis
response to peptide hormone
signal transduction by protein phosphorylation
axon development
cell morphogenesis involved in neuron differentiation
modulation of chemical synaptic transmission
regulation of trans-synaptic signaling
response to peptide
neuron projection morphogenesis
plasma membrane bounded cell projection morphogenesis
cell projection morphogenesis
transmembrane receptor protein tyrosine kinase signaling pathway
cell part morphogenesis
chemotaxis
taxis
cell morphogenesis involved in differentiation
cellular response to organonitrogen compound
cellular response to hormone stimulus
cellular response to nitrogen compound
neuron projection development
enzyme linked receptor protein signaling pathway
cell morphogenesis
neuron development
cellular component morphogenesis