RAB11B
Gene Information
- Official Symbol: RAB11B
- Official Name: RAB11B, member RAS oncogene family
- Aliases and Previous Symbols: N/A
- Entrez ID: 9230
- UniProt: Q15907
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: N/A
Pfam Domains GO Terms
Pfam Domains
| Arf |
| Miro |
| Ras |
GO Terms
| constitutive secretory pathway |
| amyloid-beta clearance by transcytosis |
| insulin secretion involved in cellular response to glucose stimulus |
| regulation of endocytic recycling |
| cellular response to acidic pH |
| receptor recycling |
| anchored component of synaptic vesicle membrane |
| myosin V binding |
| transcytosis |
| melanosome transport |
| amyloid-beta clearance |
| pigment granule transport |
| establishment of melanosome localization |
| establishment of pigment granule localization |
| response to acidic pH |
| cellular response to pH |
| melanosome localization |
| pigment granule localization |
| retrograde transport, endosome to plasma membrane |
| transferrin transport |
| regulation of protein localization to cell surface |
| insulin secretion |
| response to pH |
| cellular pigmentation |
| peptide hormone secretion |
| phagocytic vesicle |
| cellular response to glucose stimulus |
| cellular response to hexose stimulus |
| iron ion transport |
| hormone secretion |
| Rab protein signal transduction |
| cellular response to monosaccharide stimulus |
| phagocytic vesicle membrane |
| GDP binding |
| cellular response to carbohydrate stimulus |
| hormone transport |
| recycling endosome membrane |
| cellular glucose homeostasis |
| pigmentation |
| vesicle-mediated transport to the plasma membrane |
| regulation of anion transport |
| receptor metabolic process |
| recycling endosome |
| synaptic vesicle |
| transition metal ion transport |
| response to glucose |
| response to hexose |
| response to monosaccharide |
| protein secretion |
| establishment of protein localization to extracellular region |
| protein localization to extracellular region |
| signal release |
| response to carbohydrate |
| peptide secretion |
| establishment of vesicle localization |
| glucose homeostasis |
| vesicle localization |
| carbohydrate homeostasis |
| endosomal transport |
| Ras protein signal transduction |
| establishment of protein localization to membrane |
| endosome |
| cadherin binding |
| cellular response to environmental stimulus |
| cellular response to abiotic stimulus |
| small GTPase mediated signal transduction |
| GTPase activity |
| regulation of intracellular transport |
| post-translational protein modification |
| establishment of organelle localization |
| GTP binding |
| protein localization to membrane |
| regulation of hormone levels |
| regulation of cellular protein localization |
| cell junction |
| regulation of vesicle-mediated transport |
| organelle localization |
| metal ion transport |
| regulation of ion transport |
| regulated exocytosis |
| cellular chemical homeostasis |
| exocytosis |
| cation transport |
| cellular homeostasis |
| regulation of cellular localization |
| intracellular protein transport |
| secretion by cell |
| regulation of protein localization |
| export from cell |
| cellular response to oxygen-containing compound |
| chemical homeostasis |
| cell-cell signaling |
| secretion |
| response to abiotic stimulus |
| ion transport |
| protein transport |
| intracellular transport |
| peptide transport |
| response to oxygen-containing compound |
| amide transport |
| cellular protein localization |
| cellular macromolecule localization |
| establishment of protein localization |
| homeostatic process |
| intracellular signal transduction |
| establishment of localization in cell |
| nitrogen compound transport |
| regulation of transport |
| vesicle-mediated transport |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
| Screen | Score |
|---|---|
| Clomiphene 4.4μM R02 exp68 | 1.88 |
| Vemurafenib 6.6μM R02 exp89 | 2.06 |
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Essentiality in NALM6
- Essentiality Rank: 12173
- Expression level (log2 read counts): 5.02
Expression Distribution
RAB11B Expression in NALM6 Cells: 5.02
