RAB15

Entrez Summary: N/A
UniProt Summary: May act in concert with RAB3A in regulating aspects of synaptic vesicle membrane flow within the nerve terminal. {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

vesicle docking involved in exocytosis
positive regulation of regulated secretory pathway
vesicle docking
exocytic process
Rab protein signal transduction
positive regulation of exocytosis
synaptic vesicle
protein secretion
establishment of protein localization to extracellular region
regulation of regulated secretory pathway
protein localization to extracellular region
organelle localization by membrane tethering
peptide secretion
membrane docking
protein localization to plasma membrane
cilium
endosome membrane
regulation of exocytosis
protein localization to cell periphery
Ras protein signal transduction
endosome
small GTPase mediated signal transduction
GTPase activity
GTP binding
positive regulation of secretion by cell
positive regulation of secretion
protein localization to membrane
regulation of vesicle-mediated transport
organelle localization
perinuclear region of cytoplasm
regulation of secretion by cell
exocytosis
regulation of secretion
positive regulation of transport
intracellular protein transport
secretion by cell
export from cell
secretion
protein transport
intracellular transport