RABEP2

Entrez Summary: N/A
UniProt Summary: Plays a role in membrane trafficking and in homotypic early endosome fusion. {ECO:0000269|PubMed:9524116}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Rab5-bind
Rabaptin

regulation of cilium assembly
ciliary basal body
growth factor activity
regulation of plasma membrane bounded cell projection assembly
regulation of cell projection assembly
regulation of organelle assembly
early endosome
GTPase activator activity
positive regulation of GTPase activity
regulation of GTPase activity
centrosome
endocytosis
import into cell
intracellular membrane-bounded organelle
regulation of plasma membrane bounded cell projection organization
regulation of cell projection organization
positive regulation of hydrolase activity
regulation of cellular component biogenesis
cell projection organization
regulation of hydrolase activity
regulation of organelle organization
positive regulation of catalytic activity
protein transport
peptide transport
amide transport
establishment of protein localization
positive regulation of molecular function
nitrogen compound transport
vesicle-mediated transport