RBM19

Entrez Summary: N/A
UniProt Summary: Plays a role in embryo pre-implantation development. {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 462/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	1/1
909776.0	0/1
bile duct	24/28
blood	12/28
bone	19/26
breast	23/33
central nervous system	40/56
cervix	1/4
colorectal	12/17
esophagus	9/13
fibroblast	1/1
gastric	9/16
kidney	10/21
liver	12/20
lung	49/75
lymphocyte	8/16
ovary	15/26
pancreas	15/24
peripheral nervous system	8/16
plasma cell	9/15
prostate	1/1
skin	12/24
soft tissue	6/9
thyroid	0/2
upper aerodigestive	10/22
urinary tract	16/29
uterus	1/5

Expression Distribution

Screen	Score
Phenformin 20μM R03 exp143	-2.3
Momordin-Ic 10μM R08 exp506	1.72
4-Nitroquinoline-1-oxide 0.5μM R08 exp446	2.06

mRNA cis splicing, via spliceosome
positive regulation of embryonic development
regulation of alternative mRNA splicing, via spliceosome
regulation of mRNA splicing, via spliceosome
chromosome
regulation of embryonic development
regulation of RNA splicing
regulation of mRNA processing
mRNA splicing, via spliceosome
RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
RNA splicing, via transesterification reactions
regulation of mRNA metabolic process
RNA splicing
nuclear speck
mRNA processing
mRNA metabolic process
nucleolus
RNA processing
positive regulation of developmental process
RNA binding
RNA metabolic process
positive regulation of multicellular organismal process
membrane
gene expression