RCBTB1

Gene Information
  • Official Symbol: RCBTB1
  • Official Name: RCC1 and BTB domain containing protein 1
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 55213
  • UniProt: Q8NDN9
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: This gene encodes a protein with an N-terminal RCC1 domain and a C-terminal BTB (broad complex, tramtrack and bric-a-brac) domain. In rat, over-expression of this gene in vascular smooth muscle cells induced cellular hypertrophy. In rat, the C-terminus of RCBTB1 interacts with the angiotensin II receptor-1A. In humans, this gene maps to a region of chromosome 13q that is frequently deleted in B-cell chronic lymphocytic leukemia and other lymphoid malignancies. [provided by RefSeq, Jul 2008].
  • UniProt Summary: May be involved in cell cycle regulation by chromatin remodeling. {ECO:0000269|PubMed:11306461}.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 15032
  • Expression level (log2 read counts): 6.51

Expression Distribution

  • Last modified: 2026/01/07 22:36
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