RCVRN

Entrez Summary: N/A
UniProt Summary: Seems to be implicated in the pathway from retinal rod guanylate cyclase to rhodopsin. May be involved in the inhibition of the phosphorylation of rhodopsin in a calcium-dependent manner. The calcium-bound recoverin prolongs the photoresponse.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

calcium sensitive guanylate cyclase activator activity
positive regulation of guanylate cyclase activity
regulation of guanylate cyclase activity
positive regulation of nucleotide biosynthetic process
positive regulation of purine nucleotide biosynthetic process
positive regulation of cyclase activity
positive regulation of lyase activity
regulation of purine nucleotide biosynthetic process
regulation of nucleotide biosynthetic process
regulation of cyclase activity
phototransduction
regulation of lyase activity
positive regulation of nucleotide metabolic process
positive regulation of purine nucleotide metabolic process
detection of light stimulus
regulation of purine nucleotide metabolic process
regulation of nucleotide metabolic process
detection of external stimulus
detection of abiotic stimulus
positive regulation of small molecule metabolic process
visual perception
sensory perception of light stimulus
regulation of calcium ion transport
response to light stimulus
regulation of metal ion transport
dendrite
regulation of small molecule metabolic process
response to radiation
detection of stimulus
regulation of ion transport
calcium ion binding
sensory perception
positive regulation of phosphorus metabolic process
positive regulation of phosphate metabolic process
response to abiotic stimulus
nervous system process
positive regulation of catalytic activity
positive regulation of molecular function
regulation of phosphate metabolic process
regulation of phosphorus metabolic process