RDH11

Entrez Summary: The protein encoded by this gene is an NADPH-dependent retinal reductase and a short-chain dehydrogenase/reductase. The encoded protein has no steroid dehydrogenase activity. [provided by RefSeq, Nov 2011].
UniProt Summary: N/A

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

KR
adh short

cellular detoxification of aldehyde
cellular response to aldehyde
NADP-retinol dehydrogenase activity
retinal metabolic process
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
retinol dehydrogenase activity
retinol metabolic process
cellular aldehyde metabolic process
primary alcohol metabolic process
cellular detoxification
retinoid metabolic process
diterpenoid metabolic process
terpenoid metabolic process
cellular hormone metabolic process
detoxification
isoprenoid metabolic process
hormone metabolic process
cellular response to toxic substance
alcohol metabolic process
organic hydroxy compound metabolic process
response to toxic substance
regulation of hormone levels
endoplasmic reticulum membrane
cellular lipid metabolic process
oxidation-reduction process
cellular response to oxygen-containing compound
lipid metabolic process
response to oxygen-containing compound
small molecule metabolic process