RFPL1

Gene Information

Official Symbol: RFPL1
Official Name: ret finger protein like 1
Aliases and Previous Symbols: N/A
Entrez ID: 5988
UniProt: O75677
Interactions: BioGRID
PubMed articles: Open PubMed
OMIM: Open OMIM

Function Summary

Entrez Summary: N/A
UniProt Summary: N/A

Pfam Domains GO Terms

CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Essentiality in NALM6

Essentiality Rank: 6421
Expression level (log2 read counts): -7.68

Expression Distribution

SPRY
RDM

positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis
regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis
positive regulation of execution phase of apoptosis
negative regulation of cell division
regulation of execution phase of apoptosis
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
negative regulation of G2/M transition of mitotic cell cycle
positive regulation of ubiquitin-dependent protein catabolic process
negative regulation of cell cycle G2/M phase transition
positive regulation of proteasomal protein catabolic process
positive regulation of proteolysis involved in cellular protein catabolic process
regulation of proteasomal ubiquitin-dependent protein catabolic process
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
positive regulation of cellular protein catabolic process
positive regulation of cysteine-type endopeptidase activity
regulation of ubiquitin-dependent protein catabolic process
regulation of cell division
positive regulation of endopeptidase activity
regulation of proteasomal protein catabolic process
positive regulation of peptidase activity
regulation of G2/M transition of mitotic cell cycle
regulation of cell cycle G2/M phase transition
negative regulation of mitotic cell cycle phase transition
regulation of cysteine-type endopeptidase activity involved in apoptotic process
regulation of proteolysis involved in cellular protein catabolic process
positive regulation of protein catabolic process
negative regulation of cell cycle phase transition
regulation of cysteine-type endopeptidase activity
regulation of cellular protein catabolic process
negative regulation of mitotic cell cycle
negative regulation of cell cycle process
positive regulation of proteolysis
positive regulation of cellular catabolic process
regulation of protein catabolic process
regulation of mitotic cell cycle phase transition
regulation of endopeptidase activity
positive regulation of catabolic process
regulation of peptidase activity
regulation of cell cycle phase transition
negative regulation of cell cycle