RHOJ

Entrez Summary: N/A
UniProt Summary: GTP-binding protein with GTPase activity. Elicits the formation of F-actin-rich structures in fibroblasts and is involved in the regulation of cell morphology (By similarity). {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Miro
Ras

retina vasculature morphogenesis in camera-type eye
retina vasculature development in camera-type eye
positive regulation of cell migration involved in sprouting angiogenesis
regulation of cell migration involved in sprouting angiogenesis
positive regulation of sprouting angiogenesis
positive regulation of blood vessel endothelial cell migration
regulation of sprouting angiogenesis
Rho protein signal transduction
regulation of blood vessel endothelial cell migration
cell projection
positive regulation of endothelial cell migration
cell cortex
retina development in camera-type eye
positive regulation of epithelial cell migration
regulation of cell shape
regulation of endothelial cell migration
positive regulation of angiogenesis
positive regulation of vasculature development
establishment or maintenance of cell polarity
regulation of epithelial cell migration
actin filament organization
Ras protein signal transduction
regulation of angiogenesis
camera-type eye development
angiogenesis
small GTPase mediated signal transduction
regulation of vasculature development
GTPase activity
regulation of actin cytoskeleton organization
regulation of small GTPase mediated signal transduction
eye development
visual system development
sensory system development
regulation of actin filament-based process
GTP binding
blood vessel morphogenesis
supramolecular fiber organization
cell projection assembly
protein kinase binding
blood vessel development