RNASE10

Entrez Summary: N/A
UniProt Summary: Secreted proximal epididymal protein required for post- testicular sperm maturation and male fertility. May be involved in sperm adhesion to the egg zona pellucida. Does not have ribonuclease activity (By similarity). {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

positive regulation of flagellated sperm motility
positive regulation of cilium-dependent cell motility
regulation of flagellated sperm motility
ribonuclease activity
regulation of cilium-dependent cell motility
regulation of fertilization
heterotypic cell-cell adhesion
positive regulation of reproductive process
single fertilization
RNA phosphodiester bond hydrolysis
regulation of reproductive process
fertilization
nucleic acid binding
positive regulation of cell-cell adhesion
nucleic acid phosphodiester bond hydrolysis
regulation of cell-cell adhesion
positive regulation of cell adhesion
cell-cell adhesion
positive regulation of cell motility
positive regulation of cellular component movement
positive regulation of locomotion
regulation of cell adhesion
regulation of multi-organism process
sexual reproduction
regulation of cell motility
cell adhesion
biological adhesion
regulation of locomotion
multi-organism reproductive process
regulation of cellular component movement
reproductive process
reproduction
RNA metabolic process
extracellular region