RPS6KB2

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

ribosomal protein S6 kinase activity
TOR signaling
positive regulation of translational initiation
protein kinase B signaling
peptide binding
regulation of translational initiation
positive regulation of translation
positive regulation of cellular amide metabolic process
protein kinase activity
regulation of translation
protein serine/threonine kinase activity
translation
regulation of cellular amide metabolic process
peptide biosynthetic process
posttranscriptional regulation of gene expression
amide biosynthetic process
peptide metabolic process
cellular amide metabolic process
protein phosphorylation
phosphorylation
organonitrogen compound biosynthetic process
ATP binding
positive regulation of cellular protein metabolic process
cellular nitrogen compound biosynthetic process
intracellular signal transduction
positive regulation of protein metabolic process
cellular macromolecule biosynthetic process
macromolecule biosynthetic process
positive regulation of macromolecule biosynthetic process
positive regulation of cellular biosynthetic process
positive regulation of gene expression
gene expression
positive regulation of biosynthetic process