RSPH1

• Official Symbol: RSPH1
• Official Name: radial spoke head component 1
• Aliases and Previous Symbols: N/A
• Entrez ID: 89765
• UniProt: Q8WYR4
• Interactions: BioGRID
• PubMed articles: Open PubMed
• OMIM: Open OMIM

• Entrez Summary: This gene encodes a male meiotic metaphase chromosome-associated acidic protein. This gene is expressed in tissues with motile cilia or flagella, including the trachea, lungs, airway brushings, and testes. Mutations in this gene result in primary ciliary dyskinesia-24. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2014].
• UniProt Summary: May play an important role in male meiosis (By similarity). It is necessary for proper building of the axonemal central pair and radial spokes. {ECO:0000250, ECO:0000269|PubMed:23993197}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

• Essentiality Rank: 2290
• Expression level (log2 read counts): -0.51

Expression Distribution

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RSPH1 Expression in NALM6 Cells: -0.51