SCARF2
Gene Information
- Official Symbol: SCARF2
- Official Name: scavenger receptor class F member 2
- Aliases and Previous Symbols: N/A
- Entrez ID: 91179
- UniProt: Q96GP6
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: The protein encoded by this gene is similar to SCARF1/SREC-I, a scavenger receptor protein that mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL). This protein has only little activity of internalizing modified low density lipoproteins (LDL), but it can interact with SCARF1 through its extracellular domain. The association of this protein with SCARF1 is suppressed by the presence of scavenger ligands. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008].
- UniProt Summary: Probable adhesion protein, which mediates homophilic and heterophilic interactions. In contrast to SCARF1, it poorly mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL) (By similarity). {ECO:0000250}.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 7951
- Expression level (log2 read counts): -1.04
SCARF2 Expression in NALM6 Cells: -1.04
