SDAD1

Entrez Summary: N/A
UniProt Summary: Required for 60S pre-ribosomal subunits export to the cytoplasm. {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 39/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	2/28
blood	0/28
bone	2/26
breast	0/33
central nervous system	5/56
cervix	0/4
colorectal	1/17
esophagus	0/13
fibroblast	0/1
gastric	1/16
kidney	3/21
liver	0/20
lung	6/75
lymphocyte	2/16
ovary	0/26
pancreas	0/24
peripheral nervous system	1/16
plasma cell	1/15
prostate	0/1
skin	1/24
soft tissue	2/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
ABT-702 5μM R06 exp261	-1.83
Vinorelbine 0.001μM R05 exp249	1.84

SDA1
NUC130 3NT

ribosomal large subunit export from nucleus
ribosomal subunit export from nucleus
ribosome localization
rRNA-containing ribonucleoprotein complex export from nucleus
ribosomal large subunit biogenesis
ribonucleoprotein complex export from nucleus
ribonucleoprotein complex localization
RNA export from nucleus
protein export from nucleus
nuclear export
RNA transport
nucleic acid transport
establishment of RNA localization
RNA localization
nucleobase-containing compound transport
protein-containing complex localization
nucleocytoplasmic transport
nuclear transport
ribosome biogenesis
establishment of organelle localization
ribonucleoprotein complex biogenesis
actin cytoskeleton organization
actin filament-based process
organelle localization
molecular function
nucleolus
intracellular protein transport
cytoskeleton organization
protein transport
intracellular transport
peptide transport
amide transport
cellular protein localization
cellular macromolecule localization
establishment of protein localization
establishment of localization in cell
nitrogen compound transport