SDS

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

L-threonine ammonia-lyase activity
L-serine ammonia-lyase activity
L-serine catabolic process
threonine catabolic process
L-threonine catabolic process to glycine
pyruvate biosynthetic process
threonine metabolic process
L-serine metabolic process
serine family amino acid catabolic process
glycine metabolic process
aspartate family amino acid catabolic process
serine family amino acid metabolic process
gluconeogenesis
hexose biosynthetic process
aspartate family amino acid metabolic process
monosaccharide biosynthetic process
pyridoxal phosphate binding
pyruvate metabolic process
neurotransmitter metabolic process
alpha-amino acid catabolic process
glucose metabolic process
cellular amino acid catabolic process
carbohydrate biosynthetic process
drug catabolic process
hexose metabolic process
monocarboxylic acid biosynthetic process
monosaccharide metabolic process
alpha-amino acid metabolic process
organic acid catabolic process
carboxylic acid catabolic process
carboxylic acid biosynthetic process
organic acid biosynthetic process
cellular amino acid metabolic process
regulation of neurotransmitter levels
small molecule catabolic process
carbohydrate metabolic process
drug metabolic process
monocarboxylic acid metabolic process
small molecule biosynthetic process
protein homodimerization activity