SDSL

Entrez Summary: N/A
UniProt Summary: Has low serine dehydratase and threonine dehydratase activity.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

L-threonine ammonia-lyase activity
L-serine ammonia-lyase activity
threonine catabolic process
L-serine catabolic process
L-threonine catabolic process to glycine
threonine metabolic process
L-serine metabolic process
serine family amino acid catabolic process
glycine metabolic process
aspartate family amino acid catabolic process
serine family amino acid metabolic process
aspartate family amino acid metabolic process
pyridoxal phosphate binding
neurotransmitter metabolic process
alpha-amino acid catabolic process
cellular amino acid catabolic process
drug catabolic process
alpha-amino acid metabolic process
carboxylic acid catabolic process
organic acid catabolic process
cellular amino acid metabolic process
regulation of neurotransmitter levels
small molecule catabolic process
drug metabolic process
molecular function
carboxylic acid metabolic process
oxoacid metabolic process
organic acid metabolic process
organonitrogen compound catabolic process
identical protein binding
small molecule metabolic process
organic substance catabolic process
cellular catabolic process