SEC16B

Entrez Summary: N/A
UniProt Summary: Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus and for normal transitional endoplasmic reticulum (tER) organization. {ECO:0000269|PubMed:17192411}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Sec16
Sec16 C

protein localization to endoplasmic reticulum exit site
peroxisome fission
positive regulation of protein exit from endoplasmic reticulum
regulation of protein exit from endoplasmic reticulum
endoplasmic reticulum exit site
ER to Golgi transport vesicle membrane
endoplasmic reticulum organization
COPII vesicle coating
vesicle targeting, rough ER to cis-Golgi
vesicle coating
COPII-coated vesicle budding
vesicle targeting, to, from or within Golgi
Golgi vesicle budding
peroxisome organization
vesicle targeting
vesicle budding from membrane
Golgi organization
protein localization to endoplasmic reticulum
positive regulation of intracellular protein transport
establishment of vesicle localization
vesicle localization
positive regulation of intracellular transport
endoplasmic reticulum to Golgi vesicle-mediated transport
regulation of intracellular protein transport
vesicle organization
organelle fission
positive regulation of cellular protein localization
regulation of intracellular transport
establishment of organelle localization
Golgi vesicle transport
endomembrane system organization
positive regulation of protein transport
positive regulation of establishment of protein localization
regulation of cellular protein localization
organelle localization
Golgi membrane
intracellular membrane-bounded organelle
regulation of protein transport
protein localization to organelle
regulation of peptide transport