SEC31B

Entrez Summary: N/A
UniProt Summary: As a component of the coat protein complex II (COPII), may function in vesicle budding and cargo export from the endoplasmic reticulum. {ECO:0000269|PubMed:16495487}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

vesicle coat
COPII-coated vesicle cargo loading
COPII vesicle coat
vesicle cargo loading
endoplasmic reticulum exit site
endoplasmic reticulum organization
COPII-coated vesicle budding
Golgi vesicle budding
localization within membrane
vesicle budding from membrane
structural molecule activity
endoplasmic reticulum to Golgi vesicle-mediated transport
vesicle organization
Golgi vesicle transport
endomembrane system organization
Golgi membrane
membrane organization
endoplasmic reticulum membrane
intracellular protein transport
protein transport
intracellular transport
peptide transport
amide transport
cellular protein localization
cellular macromolecule localization
establishment of protein localization
establishment of localization in cell
nitrogen compound transport
vesicle-mediated transport