SELM

Entrez Summary: N/A
UniProt Summary: May function as a thiol-disulfide oxidoreductase that participates in disulfide bond formation. {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

corticosterone secretion
glucocorticoid secretion
corticosteroid hormone secretion
steroid hormone secretion
lipid export from cell
endocrine hormone secretion
response to selenium ion
adipose tissue development
endocrine process
hormone secretion
hormone transport
multicellular organism growth
organic hydroxy compound transport
signal release
hormone metabolic process
connective tissue development
lipid transport
lipid localization
developmental growth
growth
regulation of hormone levels
response to inorganic substance
perinuclear region of cytoplasm
Golgi apparatus
secretion by cell
endoplasmic reticulum
export from cell
cell-cell signaling
secretion
tissue development
system process