SH3BP5

Gene Information
  • Official Symbol: SH3BP5
  • Official Name: SH3 domain binding protein 5
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 9467
  • UniProt: O60239
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: N/A
  • UniProt Summary: Inhibits the auto- and transphosphorylation activity of BTK. Plays a negative regulatory role in BTK-related cytoplasmic signaling in B-cells. May be involved in BCR-induced apoptotic cell death. {ECO:0000269|PubMed:10339589, ECO:0000269|PubMed:9571151}.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 8971
  • Expression level (log2 read counts): 2.36

Expression Distribution

  • Last modified: 2026/01/07 22:37
  • by 127.0.0.1