SH3YL1

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
UMK57 0.6μM R03 exp107	-1.89
Talazoparib 0.006μM R06 exp299	-1.78

regulation of ruffle assembly
phosphatase binding
phosphatidylinositol binding
ruffle membrane
phosphatidylinositol biosynthetic process
phosphatidylinositol metabolic process
regulation of plasma membrane bounded cell projection assembly
regulation of cell projection assembly
glycerophospholipid biosynthetic process
glycerolipid biosynthetic process
phospholipid biosynthetic process
glycerophospholipid metabolic process
phospholipid metabolic process
glycerolipid metabolic process
organophosphate biosynthetic process
lipid biosynthetic process
regulation of plasma membrane bounded cell projection organization
regulation of cell projection organization
organophosphate metabolic process
cellular lipid metabolic process
regulation of cellular component biogenesis
lipid metabolic process