SLC17A1

Entrez Summary: N/A
UniProt Summary: Important for the resorption of phosphate by the kidney. May be involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane. Plays a role in urate transport in the kidney (PubMed:27906618). {ECO:0000269|PubMed:27906618}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

urate transport
sodium-dependent phosphate transport
sodium-dependent phosphate transmembrane transporter activity
sialic acid transmembrane transporter activity
sialic acid transport
urate metabolic process
phosphate ion transmembrane transport
phosphate ion transport
symporter activity
carbohydrate derivative transport
inorganic anion transmembrane transport
sodium ion transport
inorganic anion transport
lysosome
anion transmembrane transport
organic acid transport
carboxylic acid transport
apical plasma membrane
purine-containing compound metabolic process
monovalent inorganic cation transport
organic anion transport
anion transport
metal ion transport
inorganic ion transmembrane transport
cation transport
ion transmembrane transport
organic acid metabolic process
transmembrane transport
ion transport
integral component of plasma membrane
small molecule metabolic process
nitrogen compound transport
membrane