SLC26A9

Entrez Summary: N/A
UniProt Summary: DIDS- and thiosulfate- sensitive anion exchanger mediating chloride, sulfate and oxalate transport. Mediates chloride/bicarbonate exchange or chloride-independent bicarbonate extrusion thus assuring bicarbonate secretion. Inhibited by ammonium and thiosulfate. {ECO:0000269|PubMed:11834742, ECO:0000269|PubMed:15800055}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Sulfate transp
STAS

oxalate transmembrane transporter activity
oxalate transport
secondary active sulfate transmembrane transporter activity
bicarbonate transmembrane transporter activity
sulfate transmembrane transporter activity
sulfate transmembrane transport
chloride transmembrane transporter activity
sulfate transport
anion:anion antiporter activity
bicarbonate transport
sulfur compound transport
chloride channel activity
dicarboxylic acid transport
ATPase binding
chloride transmembrane transport
chloride transport
inorganic anion transmembrane transport
inorganic anion transport
anion transmembrane transport
organic acid transport
carboxylic acid transport
apical plasma membrane
organic anion transport
anion transport
cell surface
inorganic ion transmembrane transport
ion transmembrane transport
transmembrane transport
ion transport
integral component of plasma membrane
positive regulation of gene expression