SLC35A1
Gene Information
- Official Symbol: SLC35A1
- Official Name: solute carrier family 35 member A1
- Aliases and Previous Symbols: N/A
- Entrez ID: 10559
- UniProt: P78382
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: The protein encoded by this gene is found in the membrane of the Golgi apparatus, where it transports nucleotide sugars into the Golgi. One such nucleotide sugar is CMP-sialic acid, which is imported into the Golgi by the encoded protein and subsequently glycosylated. Defects in this gene are a cause of congenital disorder of glycosylation type 2F (CDG2F). Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Dec 2009].
- UniProt Summary: Transports CMP-sialic acid from the cytosol into Golgi vesicles where glycosyltransferases function.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 14278
- Expression level (log2 read counts): 5.33
SLC35A1 Expression in NALM6 Cells: 5.33
