SLC6A7

Entrez Summary: N/A
UniProt Summary: Terminates the action of proline by its high affinity sodium-dependent reuptake into presynaptic terminals.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

proline:sodium symporter activity
L-proline transmembrane transporter activity
proline transmembrane transport
proline transport
neurotransmitter:sodium symporter activity
neutral amino acid transport
amino acid transmembrane transport
amino acid transport
organic acid transmembrane transport
carboxylic acid transmembrane transport
neurotransmitter transport
anion transmembrane transport
carboxylic acid transport
organic acid transport
organic anion transport
anion transport
cation transmembrane transport
cation transport
ion transmembrane transport
transmembrane transport
ion transport
integral component of plasma membrane
nitrogen compound transport
membrane