SMIM11A [The Human Chemical-Genetic Interaction Map Project]

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======= SMIM11A =======


== Gene Information ==
  * **<color #00a2e8>Official Symbol</color>**: SMIM11A
  * **<color #00a2e8>Official Name</color>**: small integral membrane protein 11A
  * **<color #00a2e8>Aliases and Previous Symbols</color>**: N/A
  * **<color #00a2e8>Entrez ID</color>**: [[https://www.ncbi.nlm.nih.gov/gene/?term=54065|54065]]
  * **<color #00a2e8>UniProt</color>**: [[https://www.uniprot.org/uniprot/P58511|P58511]]
  * **<color #00a2e8>Interactions</color>**: [[https://thebiogrid.org/search.php?search=SMIM11A&organism=9606|BioGRID]]
  * **<color #00a2e8>PubMed articles</color>**: [[https://www.ncbi.nlm.nih.gov/pubmed/?term=gene%20SMIM11A|Open PubMed]]
  * **<color #00a2e8>OMIM</color>**:  N/A

== Function Summary ==
  * **<color #00a2e8>Entrez Summary</color>**: N/A
  * **<color #00a2e8>UniProt Summary</color>**: N/A

<button type='default' size='sm' modal='Pfam_Domains'>Pfam Domains</button>
<button type='primary' size='sm' modal='GO_terms'>GO Terms</button>


<modal id='Pfam_Domains' size='lg' title='Pfam Domains'>
No Pfam Domain information is available for this gene.
</modal>

<modal id='GO_terms' size='lg' title='GO Terms'>
|cellular component|
|molecular function|
</modal>
\\

 === CRISPR Data ===
<button type='primary' size='small' modal='Compound_Hit'>Compound Hit</button>
<button type='default' size='small' modal='Most_Correlated_Genes'>Most Correlated Genes in Chemogenomics</button>
<button type='primary' size='small' modal='Essential_Avana'>Tissues where Essential in the Avana Dataset (DepMap 20Q1)</button>

<modal id='Compound_Hit' size='lg' title='Compound Hit'>
^Screen^Score^
|[[:results:exp466|Cannabidiol 20μM R08 exp466]]|-2.62|
|[[:results:exp538|ZLN024 50μM R08 exp538]]|-2.25|
|[[:results:exp519|RS-1 10μM R08 exp519]]|-1.79|
|[[:results:exp303|39°C R06 exp303]]|-1.75|
|[[:results:exp264|Arsenate 40μM R06 exp264]]|-1.7|
|[[:results:exp220|BAY-598 4μM R05 exp220]]|1.7|
|[[:results:exp529|Thimerosal 0.85μM R08 exp529]]|1.7|
|[[:results:exp312|2-Methoxyestradiol 0.55 to 1μM on day4 R07 exp312]]|1.75|
|[[:results:exp474|CR131-b 0.005μM R08 exp474]]|1.77|
|[[:results:exp459|Bleomycin 5μM R08 exp459]]|1.8|
|[[:results:exp232|Epothilone-D 0.004 to 0.006μM on day4 R05 exp232]]|1.8|
|[[:results:exp536|Vitamin-D3 40μM R08 exp536]]|1.82|
|[[:results:exp82|Torin1 0.08μM R02 exp82]]|1.85|
|[[:results:exp492|iCRT14 30μM R08 exp492]]|1.86|
|[[:results:exp241|QNZ 0.01μM R05 exp241]]|1.96|
|[[:results:exp448|Ammonium tetrathiomolybdate 10μM R08 exp448]]|2.02|
|[[:results:exp29|Rapamycin 1μM R00 exp29]]|2.04|
|[[:results:exp208|Vinblastine 0.015μM R05 exp208]]|2.09|
|[[:results:exp126|GSK461364A 0.1μM R03 exp126]]|2.17|
|[[:results:exp183|IU1-C 25μM R04 exp183]]|2.54|
</modal>

<modal id='Most_Correlated_Genes' size='lg' title='Most Correlated Genes in Chemogenomics'>
No correlation found to any other genes in chemogenomics.
</modal>

<modal id='Essential_Avana' size='lg' title='Tissues where Essential in the Avana Dataset (DepMap 20Q1)'>
Global Fraction of Cell Lines Where Essential: 0/739
^Tissue^Fraction Of Cell Lines Where Essential^
|1290807.0|0/1|
|909776.0|0/1|
|bile duct|0/28|
|blood|0/28|
|bone|0/26|
|breast|0/33|
|central nervous system|0/56|
|cervix|0/4|
|colorectal|0/17|
|esophagus|0/13|
|fibroblast|0/1|
|gastric|0/16|
|kidney|0/21|
|liver|0/20|
|lung|0/75|
|lymphocyte|0/16|
|ovary|0/26|
|pancreas|0/24|
|peripheral nervous system|0/16|
|plasma cell|0/15|
|prostate|0/1|
|skin|0/24|
|soft tissue|0/9|
|thyroid|0/2|
|upper aerodigestive|0/22|
|urinary tract|0/29|
|uterus|0/5|
</modal>

== Essentiality in NALM6  ==
    * **<color #00a2e8>Essentiality Rank</color>**: 7482
    * **<color #00a2e8>Expression level (log2 read counts)</color>**: N/A 
<button type='primary' size='small' modal='Dist_expr'>Expression Distribution</button>
<modal id='Dist_expr' size='lg' title='SMIM11A Expression in NALM6 Cells: N/A'>
{{:chemogenomics:nalm6 dist.png?nolink |}}
</modal>