SMIM11A

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Cannabidiol 20μM R08 exp466	-2.62
ZLN024 50μM R08 exp538	-2.25
RS-1 10μM R08 exp519	-1.79
39°C R06 exp303	-1.75
Arsenate 40μM R06 exp264	-1.7
BAY-598 4μM R05 exp220	1.7
Thimerosal 0.85μM R08 exp529	1.7
2-Methoxyestradiol 0.55 to 1μM on day4 R07 exp312	1.75
CR131-b 0.005μM R08 exp474	1.77
Bleomycin 5μM R08 exp459	1.8
Epothilone-D 0.004 to 0.006μM on day4 R05 exp232	1.8
Vitamin-D3 40μM R08 exp536	1.82
Torin1 0.08μM R02 exp82	1.85
iCRT14 30μM R08 exp492	1.86
QNZ 0.01μM R05 exp241	1.96
Ammonium tetrathiomolybdate 10μM R08 exp448	2.02
Rapamycin 1μM R00 exp29	2.04
Vinblastine 0.015μM R05 exp208	2.09
GSK461364A 0.1μM R03 exp126	2.17
IU1-C 25μM R04 exp183	2.54

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

cellular component
molecular function