ZLN024 50μM R08 exp538

Mechanism of Action

Activates AMPK, allosteric

  • Class / Subclass 1: Signal Transduction / Kinase Activator

Technical Notes

Compound References

  • PubChem Name: ZLN024 hydrochloride
  • Synonyms: N/A
  • CAS #: 1883548-91-1
  • PubChem CID: 91654626
  • IUPAC: 2-[2-(2-bromo-4-methylphenoxy)ethylsulfanyl]pyrimidine;hydrochloride
  • INCHI Name: InChI=1S/C13H13BrN2OS.ClH/c1-10-3-4-12(11(14)9-10)17-7-8-18-13-15-5-2-6-16-13;/h2-6,9H,7-8H2,1H3;1H
  • INCHI Key: MMQCYIMDROWWFE-UHFFFAOYSA-N
  • Molecular Weight: 361.69
  • Canonical SMILES: CC1=CC(=C(C=C1)OCCSC2=NC=CC=N2)Br.Cl
  • Isomeric SMILES: N/A
  • Molecular Formula: C13H14BrClN2OS

Compound Supplier

  • Supplier Name: Med Chem Express
  • Catalog #: HY-16708A
  • Lot #: 14644

Compound Characterization

  • HRMS (ESI-TOF) m/z: (M+H)+ Calcd for C13H13BrN2OS 325.00047; found 325.00098

Dose Response Curve

  • Platform ID: ZLN024
  • Min: -4.5126; Max: 42.3824





IC Concentration (µM)
IC10 N/A
IC20 N/A
IC30 N/A
IC40 N/A
IC50 N/A
IC60 N/A
IC70 N/A
IC80 N/A
IC90 N/A


Screen Summary

  • Round: 08
  • Dose: 50µM
  • Days of incubation: 8
  • Doublings: 5.5
  • Numbers of reads: 15051894

Screen Results

Sensitive/Resistant hits (FDR<0.05)CRANKSScore PlotTop 30 GenesScreen SimilarityTop 30 Sensitive GO termsTop 30 Resistant GO terms
10/0ScoresViewViewViewViewView

  • Last modified: 2026/01/15 21:36
  • by 127.0.0.1