RS-1 10μM R08 exp519
Mechanism of Action
Activates DNA binding by RAD51
- Class / Subclass 1: DNA Damage, Repair and Replication / Repair Protein Activator
Technical Notes
Compound References
- PubChem Name: 3-(Benzylsulfamoyl)-4-bromo-N-(4-bromophenyl)benzamide
- Synonyms: N/A
- CAS #: 312756-74-4
- PubChem CID: 1039737
- IUPAC: 3-(benzylsulfamoyl)-4-bromo-N-(4-bromophenyl)benzamide
- INCHI Name: InChI=1S/C20H16Br2N2O3S/c21-16-7-9-17(10-8-16)24-20(25)15-6-11-18(22)19(12-15)28(26,27)23-13-14-4-2-1-3-5-14/h1-12,23H,13H2,(H,24,25)
- INCHI Key: SWKAVEUTKGKHSR-UHFFFAOYSA-N
- Molecular Weight: 524.2
- Canonical SMILES: C1=CC=C(C=C1)CNS(=O)(=O)C2=C(C=CC(=C2)C(=O)NC3=CC=C(C=C3)Br)Br
- Isomeric SMILES: N/A
- Molecular Formula: C20H16Br2N2O3S
Compound Supplier
- Supplier Name: Cayman Chemical
- Catalog #: 21037
- Lot #: N/A
Compound Characterization
- HRMS (ESI-TOF) m/z: (M+H)+ Calcd for C20H16Br2N2O3S 522.93212; found 522.93209
Dose Response Curve
Dose response curve not available.
Screen Summary
- Round: 08
- Dose: 10µM
- Days of incubation: 8
- Doublings: 5.6
- Numbers of reads: 16262228
Screen Results
| Sensitive/Resistant hits (FDR<0.05) | CRANKS | Score Plot | Top 30 Genes | Screen Similarity | Top 30 Sensitive GO terms | Top 30 Resistant GO terms |
|---|---|---|---|---|---|---|
| 0/0 | Scores |
RS-1 10μM R08 exp519
