OR2T27

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
RS-1 10μM R08 exp519	-2.04
Bafilomycin-A1 0.009μM R08 exp454	-1.93
42°C R08 exp539	-1.92
UM131593 0.1μM R01 exp58	-1.87
UM0129480 7μM R02 exp85	-1.78
Tozasertib 0.1μM R07 exp414	1.7
Temozolomide 200μM R04 exp189	1.82
Nicotinamide Riboside 100μM R03 exp139	1.93
UNC2400 2μM R03 exp156	2.2

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

detection of chemical stimulus involved in sensory perception of smell
olfactory receptor activity
sensory perception of smell
detection of chemical stimulus involved in sensory perception
detection of chemical stimulus
sensory perception of chemical stimulus
detection of stimulus involved in sensory perception
detection of stimulus
G protein-coupled receptor activity
sensory perception
G protein-coupled receptor signaling pathway
nervous system process
system process