SLC25A3
Gene Information
- Official Symbol: SLC25A3
- Official Name: solute carrier family 25 member 3
- Aliases and Previous Symbols: N/A
- Entrez ID: 5250
- UniProt: Q00325
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: The protein encoded by this gene catalyzes the transport of phosphate into the mitochondrial matrix, either by proton cotransport or in exchange for hydroxyl ions. The protein contains three related segments arranged in tandem which are related to those found in other characterized members of the mitochondrial carrier family. Both the N-terminal and C-terminal regions of this protein protrude toward the cytosol. Multiple alternatively spliced transcript variants have been isolated. [provided by RefSeq, Jul 2008].
- UniProt Summary: Transport of phosphate groups from the cytosol to the mitochondrial matrix. Phosphate is cotransported with H(+). May play a role regulation of the mitochondrial permeability transition pore (mPTP).
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 1651
- Expression level (log2 read counts): 8.71
SLC25A3 Expression in NALM6 Cells: 8.71
