SMTNL1

Entrez Summary: N/A
UniProt Summary: Plays a role in the regulation of contractile properties of both striated and smooth muscles. When unphosphorylated, may inhibit myosin dephosphorylation. Phosphorylation at Ser-299 reduces this inhibitory activity (By similarity). {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Expression Distribution

CH
CAMSAP CH

contractile fiber
tropomyosin binding
I band
protein phosphatase 1 binding
M band
positive regulation of vasoconstriction
filamentous actin
negative regulation of blood vessel diameter
regulation of vasoconstriction
positive regulation of blood circulation
regulation of tube diameter
regulation of blood vessel diameter
regulation of tube size
microtubule organizing center
vascular process in circulatory system
calmodulin binding
regulation of blood circulation
blood circulation
circulatory system process
actin cytoskeleton organization
regulation of anatomical structure size
actin filament-based process
regulation of system process
cytoskeleton organization
positive regulation of multicellular organismal process
system process