SOBP

Entrez Summary: The protein encoded by this gene is a nuclear zinc finger protein that is involved in development of the cochlea. Defects in this gene have also been linked to intellectual disability. [provided by RefSeq, Mar 2011].
UniProt Summary: Implicated in development of the cochlea. {ECO:0000250|UniProtKB:Q0P5V2}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

SUMO polymer binding
cochlea development
inner ear morphogenesis
ear morphogenesis
sensory perception of sound
sensory perception of mechanical stimulus
inner ear development
locomotory behavior
ear development
sensory organ morphogenesis
embryonic organ morphogenesis
cognition
embryonic organ development
sensory organ development
embryonic morphogenesis
behavior
animal organ morphogenesis
sensory perception
embryo development
nervous system process
system process