SPHKAP
Gene Information
- Official Symbol: SPHKAP
- Official Name: SPHK1 interactor, AKAP domain containing
- Aliases and Previous Symbols: N/A
- Entrez ID: 80309
- UniProt: Q2M3C7
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: Anchoring protein that binds preferentially to the type I regulatory subunit of c-AMP-dependent protein kinase (PKA type I) and targets it to distinct subcellular compartments. May act as a converging factor linking cAMP and sphingosine signaling pathways. Plays a regulatory role in the modulation of SPHK1. {ECO:0000269|PubMed:12080051, ECO:0000269|PubMed:20394097}.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 8553
- Expression level (log2 read counts): -4.6